Novalogy Inc. has been a prominent technology provider in the field of circadian light therapy since 2018. The AYO wearable light therapy device, has become a go-to solution and primary light intervention in numerous research studies. With advanced features such as real-time compliance tracking and sham capabilities, AYO has been at the forefront of research in this domain.
The AYO device has been integrated into 13 distinct studies, with an additional 3 studies currently in the setup phase, scheduled to commence in 2023/2024. Furthermore, since its debut in the consumer market in 2016, the AYO device has gained a global user base exceeding 50,000 customers.
The blue light properties of the AYO device conform to the reference values established by one of the most extensively clinically researched blue light therapy devices, namely the Philips GoLite BLU. Notably, the AYO device surpasses this reference lightbox in three key aspects:
1. Significantly Reduced Glare: AYO boasts up to 6 times less glare, minimizing eye annoyance and ensuring a comfortable user experience.
2. Portability and Ease of Use: AYO is designed for on-the-go use, allowing users to seamlessly incorporate light therapy into their daily routines.
3. Smart Capabilities: The device is equipped with intelligent features, enabling users to program therapy sessions to prevent misuse and uphold protocol adherence.
Blue light therapy has a well-established track record of providing a range of benefits, including improvements in sleep quality, cognitive performance, mood enhancement, and circadian rhythm regulation when appropriately timed exposure is administered. These benefits are extensively documented in various research publications.
The AYO wearable has received prestigious recognitions, including:
• Best Sleep Health & Wellness Device in 2022 by the National Sleep Foundation (NSF).
• Red Dot Award Winner in the health & wellness device category, acknowledging its exceptional design.
• Endorsements by reputable organizations such as the Society for Light Treatment and Biological Rhythms (SLTBR), the Good Light Group, and the SleepTech Council by NSF.
To ensure rigorous adherence to study protocols, our device is seamlessly integrated with the AYO science app. This intuitive application empowers participants to initiate their light therapy sessions within the programmed timeframe, receive helpful reminders, and prevent any misuse of the device.
Below is a comprehensive list of studies that have utilized the AYO device, presented in alphabetical order:
• Buffalo university, study focused on the effects of bright light therapy on circadian rhythms, sleep, and fatigue in cancer survivors.
Leading researcher: Dr. Carleara Weiss (in preparation, placebo and effective devices, participants up to 50)
• City of Hope, multiple locations, study on using circadian light therapy for sleep and cancer related fatigue.
Leading researcher: Dr. William Dale (ongoing, up to 200 participants, effective and placebo devices)
• M.D Anderson Cancer Center study on treating cancer related fatigue.
Leading researcher: Dr. Sriram Yennu (ongoing, up to 300 participants, effective and placebo devices, double blind)
• Michigan State University study on using blue light therapy for university students to improve concentration.
Lead researcher: Dr. Hanne Hoffman (80-100 participants, effective and placebo devices)
• Mount Sinai & Memorial Sloan Kettering Cancer Center study on sleep and cancer-related fatigue, led by Dr. William Redd (status: phase 2 has been internally completed, participants: 300; placebo and effective devices)
• Northwell Health, study on energy and fatigue in the general population (status: phase 1 has been internally completed, participants: 70; placebo and effective devices)
• Queensland Academy of Sport (Australia) study on improving athletic performance led by Dr. John P. Sullivan (status: terminated, participants 20, no control group, just effective devices)
• Reykjavik University study on improving sleep quality led by Professor Heiðdís B Valdimarsdóttir (status: awaiting publishing, positive findings, abstract available; effective and placebo devices)
• St. Jude study focused on the effectiveness of light therapy on pediatric cancer patients undergoing hospital recovery for 28 days, leading researcher: Dr. Andrew Elliott (in preparation; placebo and effective devices, participants: up to 50)
• University of Alabama at Birmingham clinical trial on the effects of bright light therapy on circadian rhythms in adults with type 2 diabetes. Leading researcher: Courtney M. Peterson (ongoing, up to 200 participants; effective devices only)
• University of Arizona (SCAN) and the US DoD, presumably world’s largest blue light study aimed at mood (depression), sleep and health. Lead researcher: William D. “Scott” Killgore (in preparation, approx. 400 participants/military personnel, effective and red placebo devices)
• University of California, Irvine, study focused on pilot study on treating insomnia and circadian rhythms on Alzheimer’s Disease risk patients.
Leading researcher: Ariel Neikrug (internally completed, placebo and effective devices, participants up to 50)
• US Department of Defense study on alertness, sleep and cognitive performance in the navy personnel operating in submarine environment (status: finished, internally published, positive findings, participants 50, only effective devices used).
Review of optical and usability properties: AYO vs Philips goLITE BLU
Personal Light Treatment Devices as a Viable Countermeasure for Submariner Fatigue
