Dorothy Sit, MD, is an Assistant Professor of Psychiatry at the University of Pittsburgh, Western Psychiatric Institute and Clinic. Her research focus is on novel treatment development for patients with Bipolar Disorder (BD). She recently completed a randomized control trial to examine the efficacy of light therapy for the treatment of bipolar depression. She is investigating possible changes in chronobiological rhythms (sleep, melatonin, activity levels) from light therapy in depressed patients with BD. She is launching new studies to explore early visual processing, and visual and neural markers of light therapy, in BD to examine putative novel predictors of treatment response and to further investigate the pathophysiology underlying BD. Her research also extends to the study of the phenomenology, psychopharmacology and metabolism of women with BD and Major Depressive Disorder across the life cycle (pregnancy, postpartum, menstrual cycles).