2.10 Circadian Rhythm Influences on Medical Conditions, and Risk Factors
While our literature survey has emphasized circadian factors that affect psychological and sleep disturbances, and non-drug treatment approaches that normalize the daily cycle, there...
2.09 Chronotype, Circadian Clock Phase, and Period
Night owl or lark or in-between: everyone operates on a circadian cycle referenced to day and night outdoors. There are two main ways to...
2.08 Chronotherapeutics: Light and Wake Therapy
A remarkable observation in the 1970’s—inspired by a depressed bipolar patient who stayed awake bike riding all night—was the immediate relief of deep depression...
2.07 Prospects for New Applications of Light Therapy
We are far from knowing the limits of light therapy, or the involvement of circadian timing in mental and physical illness. New exploratory applications...
2.06 Circadian Analysis of Shift Work Disorder, and Treatment Approaches
Shift workers are required to be awake and alert, often at times when the circadian clock is in its incompatible nighttime mode. The ensuing...
2.05 Circadian Analysis of Jet Lag, and Treatment Approaches
When we take a flight across time zones, our circadian timing system has no knowledge of the shift to a new light-dark cycle, so...
2.04 Circadian Properties of Melatonin and Its Relationship to Sleep
The hormone melatonin, produced by the pineal gland, is a sleep facilitator with circadian action. In the normal case, the inner clock in the...
2.03 Circadian Rhythm Sleep Disorders and Their Treatment
No one will be surprised that our sleep-wake cycle is closely related to the circadian timing system. This first became obvious in time-isolation studies...
2.02 Later Demonstrations of Light Therapy for Psychiatric Disorders
Given the success and rapid spread of light therapy for SAD, clinical researchers immediately wondered how far the simple technology could be applied. Multiple...
2.01 Seasonal Affective Disorder and Light Therapy
Light therapy for winter depression (seasonal affective disorder) was first developed and explored about 35 years ago at the US National Institute of Mental...
